This would be epic if it comes true. According to Deadline:

Even as Denis Villeneuve puts the finishing touches on the script for the next installment in the DuEven as Denis Villeneuve puts the finishing touches on the script for the next installment in the Dune franchise, the director already has his sights set on a new addition to the all-star ensemble. While sources close to the project say no formal offer has been presented, Deadline is hearing there is strong interest in Robert Pattinson joining the cast. Legendary had no comment.ne franchise, the director already has his sights set on a new addition to the all-star ensemble. While sources close to the project say no formal offer has been presented, Deadline is hearing there is strong interest in Robert Pattinson joining the cast. Legendary had no comment. [My emphasis]

This would reunite Rob with previous costars Timothée Chalamet and Zendaya, but I’m excited by the prospects of a collaboration with Florence Pugh.

Please be come to fruition.

UPDATED: According to THR:

Robert Pattinson may give Timothée Chalamet a hard time in Legendary’s upcoming Dune: Messiah. Sources say the actor has been circling the role of the chief villain in the film, one that is possibly Scytale from Frank Herbert’s books.

No offer has been made to Pattinson, whose call sheet includes starring in The Batman sequel for Matt Reeves, and appearing in Christopher Nolan’s The Odyssey.

IMDbPro have also added to Rob’s page as “rumoured” which is mighty quick for IMDbPro standards.